Treatment of a chordoma involves removing the maximum possible amount of tumor tissue via surgery. Surgery is followed by an aggressive dose of radiation therapy to kill any surrounding tumor cells. Radiation therapy is usually recommended as it reduces the risk of recurrence and also prolongs survival. In cases of advanced chordoma, chemotherapy may slow down the growth of the tumor or temporarily arrest the progression of the disease. Molecularly targeted cancer drugs are also gaining popularity as a treatment approach for chordomas.

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