Initially a conservative approach is used for the management of piriformis syndrome. This approach includes:
In patients with severe pain, corticosteroid or anesthetic injections can also be used.
In a few cases, botulism toxin injections and electrotherapy can also be considered. These helps reduce the muscle tightness. In patients not responding to the conservative approach, surgery may be considered. This involves the surgical release of the piriformis muscle and decompression of the sciatic nerve.